MetALD is a relatively new liver disease diagnosis that considers how the combination of diet and alcohol drive a unique disease phenotype. We are interested in studying this disease specifically in relation to binge drinking. Currently we are developing a novel, translatable mouse model to better understand MetALD.
Wastes generated from the alcohol industry, like brewers' spent grains and apple pomace, are significant environmental and financial burdens. However, they are also nutrient dense products with high potential for human consumption. We are seeking to understand if these products can play a role in human health, including if these wastes can be used as part of a circular food system with mealworms.
Research shows small changes to the diet can have major impacts for health. We are interested in learning why these small changes are beneficial or harmful to health. We are currently primarily focused on the role of different sweeteners on health with an emphasis on differences in antioxidant content.
Mouse studies are critical for understanding basic biology, yet nutrition is often an afterthought when designing mouse studies. We are working to continually create more translatable diet models for chronic disease research. We are currently focusing on a translatable Western diet model.